Nicole Parsley, Ph.D.

Nicole Parsley, Ph.D.
Postdoctoral Researcher

Department of Plant & Microbial Biology
4510C Thomas Hall, Raleigh, NC 27695

Lab Phone: 919.515.3882


  1. Parsley, N. C.; Smythers, A. L.; Hicks, L. M. Implementation of microfluidics for antimicrobial susceptibility assays: issues and optimization requirements. 2020. Frontiers in Cellular and Infection Microbiology. In Press.
  2. Parsley, N. C.; Williams, O. L.; Hicks, L. M. Exploring the diversity of cysteine-rich natural product peptides via MS/MS fingerprint ions. 2020. J. Am. Mass Spectrom. 31(9), 1833-1843. Cover Article.
  3. Moyer, T. B.; Parsley, N. C.; Sadecki, P. W.; Schug, W. J.; Hicks, L. M. Leveraging orthogonal mass spectrometry-based strategies for comprehensive characterization of antimicrobial peptides. 2020. Nat. Prod. Rep. In Press.
  4. Foreman, D. J.; Parsley, N. C.; Lawler, J. T.; Aryal, U. K.; Hicks, L. M.; McLuckey, S. A. Gas-phase sequencing of cyclotides: introduction of selective ring opening at dehydroalanine via ion/ion reaction. 2019. Anal. Chem. 91(24), 15608-15616.
  5. Parsley, N. C.; Sadecki, P. W.; Hartmann, C. J.; Hicks, L. M. Viola “inconspicua” no more: an analysis of antibacterial cyclotides. 2019. J. Nat. Prod. 82(9), 2537-2543.
  6. Bartges, T. E.; Heil, L. R.; Kirkpatrick, C. L.; Goldfarb, D.; Lefever, W. A.; Parsley, N. C.; Wommack, A. J.; Hicks, L. M. PepSAVI-MS reveals proline-rich antimicrobial peptide in Amaranthus tricolor. 2019. J. Nat. Prod. 82(10), 2744-2753.
  7. Kirkpatrick, C. L.; Parsley, N. C.; Bartges, T. E.; Wing, C. E.; Kommineni. S.; Kristich, C. J.; Salzman, N. H.; Patrie, S. M..; Hicks, L. M. Exploring bioactive peptides from bacterial secretomes using PepSAVI-MS: identification and characterization of Bac-21 from Enterococcus faecalis pPD1. 2018. Microb. Biotechnol. 11(5), 943-951.
  8. Parsley, N. C.; Kirkpatrick, C. L.; Crittenden, C. M.; Ghassemi Rad, J.; Hoskin, D. W.; Brodbelt, J. S.; Hicks, L. M. PepSAVI-MS reveals anticancer and antifungal cycloviolacins in Viola odorata. 2018. Phytochem. 152, 61-70. Cover Article.
  9. Kirkpatrick, C. L.; Parsley, N. C.; Bartges, T. E.; Cooke, M. E.; Evans, W. S.; Heil, L. R.; Smith T. J.; Hicks, L. M. Fungal Secretome Analysis via PepSAVI-MS: Identification of the bioactive peptide KP4 from Ustilago maydis. 2018. J. Am. Soc. Mass. Spectrom. 29(5), 859-865.
  10. Fong, J. C. N.; Rogers, A.; Michael, A. K.; Parsley, N. C.; Cornell, W. C.; Lin, Y. C.; Singh, P. K.; Hartmann, R.; Drescher, K.; Vinogradov, E.; Dietrich, L.; Partch, C. L.; Yildiz, F. H. Structural dynamics of RbmA governs plasticity of Vibrio cholerae biofilms. 2017. eLife. 6, e26163. Topic of Insight Article.
  11. Gustafson, C.L.; Parsley N.C.; Asimigil, H.; Lee, H.; Ahlbach, C.; Michael, A. K.; Xu, H.; Williams, O. L.; Davis, T. L.; Liu, A.; Partch, C.L. A slow conformational switch in the BMAL1 transactivation domain modulates circadian rhythms. 2017. Mol. Cell. 18(66), 447-457. Cover Article.
  12. Xu, H.; Gustafson, C. L.; Sammons, P. J.; Khan, S. K.; Parsley, N. C.; Ramanathan, C.; Lee, H.; Liu, A. C.; Partch, C. L. Cryptochrome 1 regulates the circadian clock through dynamic interactions with the BMAL1 C terminus. 2015. Nat. Struct. Mol. Biol. 22, 476–484.